Paxil Antidepressant Caused Weight Gain, High Cholesterol, Possibly Stillbirth

Eleven years ago, I began taking the antidepressant medication Paxil (Paroxetine, Fluxetine) for anxiety issues. Paxil is now known to cause many side effects. Weight gain and elevated LDL cholesterol are two problems commonly caused by Paxil. In 2001, Paxil was a newer antidepressant and less was known about it. A therapist had recommended that I consult my physician about trying the highly touted Paxil for my recurrent panic attacks.

Paxil did help me manage and process my panic attacks and anxiety issues. However I became increasingly alarmed over the horror stories linking Paxil with infant birth defects, miscarriage and stillborn babies.Before I had heard of Paxil's link to pregnancy and birth problems, I had taken Paxil during a pregnancy, under my Ob Gyn and midwife's direction. That pregnancy ended in stillbirth.

Paxil also caused weight gain. For the first 40 odd years of my life, I a) maintained a constant weight of 115-130 pounds even after giving birth four times and b) did not take anti-depressants. In 2003, I went on Paxil after the loss of a baby. Since then I've been steadily gaining weight. Yes, I'm getting older, yes I'm in menopause. But those two factors together are not enough to explain this rampant weight gain.

I explored thyroid issues. Initial tests showed that I suffered from some hypothyroid (sluggish, low functioning thyroid) and some hyperthyroid (overactive thyroid) issues. I took Levoxyl or Synthroid. Later test showed, however, that my thyroid was 'fine'. Studies show that the the Levoxyl threshold levels in general testing are way to broad to be accurate. So thyroid issues may still a problem.

Of course there is always the obvious weight gain issue. Too many calories, not enough exercise. For the first 40 plus years, I have been able to eat pretty much whatever I wanted and not gain weight. Well, I thought, that's clearly no longer the case. I went on a stringent vegetarian diet, no soda, few sweets, no eggs, very limited dairy and only yogurt, vegetables, whole grains, fiber, lots of water, the whole diet package. I have followed this regime for over four months. Not one pound did I lose. In fact, I gained weight.

So something was clearly wrong. I asked the doctor if antidepressants cause weight gain and found that indeed they do. Maybe that's a dumb question. Maybe I should have known. Or maybe my doctor should have told me about the weight gain. He's the one filling out the prescription with one hand and scolding me for not losing weight with the other. And you want to know what's really bizarre? My appetite has changed since being on the Paxil. In fact I have very little appetite. Food doesn't taste as good. I have lost my taste for chocolate, cheese, desserts, ice cream, all the things I used to enjoy, before antidepressants, and still I gain weight. But I can also easily binge and not notice it, thanks to the drugging Paxil.

When I googled "antidepressant weight gain" I found a deluge of comments from folks who have experienced the same issues. Now that is depressing! There are better antidepressants for avoiding weight gain. Wellbutrin has a better reputation than Paxil and Depakote. But I decided to skip the drugs and wean myself off from all the meds. I'm continuing the healthier eating program. If you want to follow the journey or have antidepressant horror stories of your own to share follow this blog.

2016 update to this post: Guess what? After quitting the drugs, calorie counting and working at weight loss, I've shed 100 pounds and 10 sizes!

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